What is plantar fascial fibromatosis?

2022 Sep 30th

There are few things more unsettling than discovering a lump on the foot. The symptoms of plantar fibromatosis can be disconcerting, the good news is that most cases can be managed effectively at home, without surgery.

Recognizing the symptoms, understanding your options for treatment, and then working with your doctor to determine how to best manage this condition will help get you back on your feet.

What is Ledderhose disease?

Plantar fascial fibromatosis is also known as Ledderhose disease. Ledderhose Disease is an uncommon form of disease that impacts the plantar fascia, which is a thick layer of tissue covering the base of the feet. Ledderhose disease is an autoimmune disease in which tiny nodules slowly develop in your legs. The nodules or bumps are non-cancerous thickenings of the ligaments.

What are Plantar Fibromas?

The technical name for these bumps would be Plantar Fibromas; fibrous nodules in the foot arch. Nodules can be embedded inside plantar fascium – a layer that extends below the heel to toe and covers the entire foot surface. Plantar fibrosis can occur in either foot at once. Generally, plantar fibromatomas are benign and do not disappear when treated. The cause of this foot disorder is still not known.

Understanding Plantar Fascial Fibromatosis

Plantar Fascial Fibromatosis are knots in vascular tissue that are found anywhere on the bottom of the foot. These knots are harmless and don't spread into other parts or cause injury. The main issue with Plantar Fibroma is that it can cause pain in the feet. Symptoms are often more painful when one steps on the nodule or presses their foot on particular shoes. Occasionally these symptoms are painful enough to make them unmanageable. The reason for removing a nodule is going to vary from doctor to doctor. Many scientists think a tear starts in the plantar fascia due to traumatic experiences.

Diagnosis of Plantar Fibroma

The diagnosis of plants fibromas can easily diagnose symptoms. Then consult the doctor to determine if the lump is benign. To diagnose plantar fasciculosis, the doctor must consult a foot doctor. They'll examine your heel and apply pressure. It may cause an aching sensation in your feet. If necessary, they can take a CT scan and an MRI to look for soft tissue masses. Sometimes a biopsy or surgical removal is needed to check the lump more carefully. Nodules of the foot shouldn't cause swelling. When you examine your own foot, you may not be able to detect plantar fibromatosis, or you may have another condition.


In MRI, Plantar Fibromas can be differentiated easily from other lesions in plantarial fascia. Ultrasound and MRI can be used to diagnose plantar fibrosis. On MRI, plantar fibromatomas are focal oval-shaped areas of disorganization within the plantar fascia, but larger, more lobulation lesions are seen throughout the plantar fascia. These lobularized lesions usually have a low signal intensity in a fibrous nature, but signals iso-sensitive in the muscle can also be seen. There are variable improvements when gdolinium administration occurs. Sagittal T-2MRI showed plantar fasciafibroma.

Non-operative management of plantar fascial fibromatosis

A variety of non-surgical treatment options are available for treating symptomatic Plantar Fascia. Many of the methods used by foot and ankle surgeons are used with differing degrees of success in treating fibrous diseases. There is low mortality associated with many of these measures.


  • Verapamil is a blocker of calcium that is primarily used for blood pressure management and also helps to metabolize the extracellular matrix. The drug inhibits collagen production and increases collagenase activity. This reduces the contracted function of myofibroblasts and other myofibroblasts. Verapamil can have anti-inflammatory properties through alteration of inflammatory-cytokine IL-6 et - 8. Anecdotally, verapamil has been used to treat cancer.
  • Estrogens have multiple functions within our bodies and can increase contractility in certain cells. Plantar Fascia treatment was therefore recommended using a new anti-estrogen medication. Although there have been no clinical trials evaluating its effectiveness, tamoxifen has been successfully tested in vitro in patients with Dupuytrinids.

Shock Therapy

  • Extracorporeal shock wave therapy (ESWT) has remained relatively undiscovered and has been used for several musculoskeletal conditions. Shockwaves mimic different mechanical loads and cause fibroblast cellular responses in tendons. It is assumed that ESWT helps stimulate tissue regrowth in tenocytes.

Steroid Injection

  • Steroid, cortisone injections and collagenase injections are commonly used as the first therapy to treat Plantar Fibroma symptoms. It reduces the size of fibromas and reduces associated pain in an ambulated area. Steroid injections reduce VCAM1 expression and change the cytokines pro-inflammatory TGF and bFGF9. These changes reduce inflammation and contraction rates as well.


  • Radiotherapy is another non-surgical method used for Plantar Fibroma treatment, but there is limited published evidence about its use. The ionizing beam can also reduce inflammation.

Operational management

Given its benign nature, foot and ankle surgeons decide on surgical procedures to relieve symptoms. Surgical indications today include pain resistance and aggressive locality for conservative therapy. Surgical intervention was considered effective since the 1950s, but there have also been concerns of possible reoccurrences when only partial removals are done. In this context, complete Plantar Feverectomy was traditionally considered an option when treating plantar fibromyalgia. Recently, three major techniques were used in surgery for plantar nodules: local and broad excision as total fasciectomy.

Anatomy and biomechanics of the plantar fascia

To understand plantar fascial fibromatosis, we first need to understand aponeurosis. Aponeurosis is a sheet of pearly white fibrous tissue that takes the place of a tendon in flat muscles having a wide area of attachment.The plantar fascial structure is a broad fibrous aponeurosis derived from the calcaneus' medial and anterior parts; and divides into five electronic slips at taralphalangeal joints and is distally inserted into the posterior portion. Plantar fascial fibromatosis usually occurs between the medium and central bands. The primary function of the fascial system is maintaining its longitudinal arch.

Signs & Symptoms of Plantar Fibroma

The characteristic sign associated with plantarfibroma is the presence of a visible lump in the arch of the foot. Over time it could grow bigger and remain the same, or additional fibroids might appear. Some patients with plantarfibromy do not experience pain. When pain occurs, shoes push a muscle into a lump, which can occur while walking or standing.

A vascular plant fibroma is an enlarged and firm bump at the arch. These lumped nodules can remain the same or expand with each successive growth. Fibromas are common in your feet. If you have fibromyalgia, you won't feel any discomfort.

What causes plantar fascial fibromatosis?

Plantar fibromatosis may result from genetic causes, medication or repetitive injury such as running. Plantar fibratosis is a relatively rare fibrous slit (nodule) located inside the plantarial skin of the heel and embedded within plantar fascial tissue. The reason for this could be repetitive stress or incidental trauma.

People with plantar fibromatosis often cannot identify definite signs or symptoms of their condition. The occurrence is unknown and can affect anybody.

What is the treatment for plantar fascial fibromatosis?

Often the pain is caused by footwear pushing against it instead of the nodules themselves. Different shoes may offer pain relief, but others may need physical therapy.

What drugs can I use? NSAID medicines like aspirin and ibuprofen will usually relieve your fibroma pain. An NSAID may reduce inflammation around your fibromyalgia, a pressure that can cause pain.

Putting ice on the affected area can reduce swelling and pain.

What is the difference between plantar fasciitis and plantar fascial fibromatosis?

The similarities between plantar fibromas and plantar fasciitis are that both affect your plantar fascia. Plantar fibromas are small growths on your plantar fascia. Plantar fasciitis is inflammation of the ligament itself. Plantar fasciitis is also one of the most common causes of heel pain.


Does plantar fibromatosis go away?

Plantar fibromatous tumors can be benign but can be treated only if correctly.

Is Ledderhose disease curable?

Ledder diseases usually have no problem going away over time, but sometimes things worsen. A bumpy foot may cause difficulty walking or sitting. The surgical treatment relieves pain and prevents Ledder disease from returning.

How do you get Ledderhose disease?

Repeated trauma has been linked with this syndrome. There hasn't been an accurate diagnosis of this disease, but there have been some reports.

How long does it take for plantar Fibroma to heal?

At least once a week, if you're allowed to keep your leg upright and keep on crutches. In the casts or with CAM boots, it should take about three days to heal this Fibroma, which can last 3-6 weeks in the lungs.

How do you treat plantar fasciitis fibromatosis?

Treatments are usually followed as follows: Medications that relieve pain without a prescription. Orthopsia (added to the footwear). Stretch. Verapamel is a lotion for feet. Injection with corticosteroids.


The optimal treatment of Plantar Fibromatosis continues to evolve with the study of various conservative treatment methods with varying degrees of effectiveness. Given its benign nature, conservative treatments are still the best first-line option in treating symptoms, but convincing long-term studies have never been conducted. A further study should be carried out to identify optimal therapy algorithms. Numerous operative options are available in cases requiring aggressive treatment, although there are uncommon recurrences.